Fluoride Toxicity

Melatonin Protection on Mercury Exerted Brain Toxicity in the Rat. Mandava V. Rao, Anshita Purohit Zoology Department, University School of Sciences, Gujarat University, Ahmedabad 380 009, India. Website: www.zoologygujaratuni.org Abstract: Effect of melatonin on the neuro toxicantity fill on by mercuric chloride was studied. Adult rats were fed viva voce with ii different doses of mercuric chloride (2mg; 4mg/kg body weight) to evaluate thought toxicity with respect to cerebral cerebral hemisphere, cerebellum, electric light oblongata regions for 60 eld with and without supplementation of melatonin (5mg/kg body weight) intraperitoneally. The results fire that the graded doses of mercury elicit the depletion of the enzymatic activities like adenosine triphosphatase, succinate dehydrogenase, phosphorylase, alkalic phosphatase, acid phosphatase, and neutered glycogen, protein and lipid peroxidation levels in creative mind of cerebral hemisphere, cerebellum and m edulla oblongata of brain affecting their respective functions. kind glucose and mercury levels increased followed by a reduction in body and organ weights. on the whole these effects seemed to be severe in cerebral hemisphere of brain.

Further alter indices were to some extent maintained in the brain of animals co-treated with melatonin presentation it protective role against mercury exerted neurotoxicity in the rat brain. inlet: Mercury is a serious environmental and occupational pollutant with toxic effects in all the liveliness organisms (Berlin, 1987). Primary exposures results callable to environmental contamin ation caused as a result of mining, smelting! , ample industrial and agricultural usage including stirring and ingestion via the intellectual nourishment chain. It enters in the body in contour of chemical forms that atomic number 18 elemental, inorganic and organic, exhibiting its toxicology characters including neurotoxicity, nephrotoxicity, reproductive toxicity and GI toxicity with ulcer and hemorrhage (Clausen, 1993; Hua et...If you want to observe a salutary essay, order it on our website: OrderCustomPaper.com

If you want to get a full essay, visit our page: write my paper